• Concomitant Temperature Stress and Immune Activation may Increase Mortality Despite Efficient Clearance of an Intracellular Bacterial Infection in Atlantic Cod 

      Larsen, Anett Kristin; Nymo, Ingebjørg Helena; Sørensen, Karen Kristine; Seppola, Marit; Rødven, Rolf; Jiménez de Bagüés, María Pilar; Al Dahouk, Sascha; Godfroid, Jacques (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-04)
      The environmental temperature has profound effects on biological systems of marine aquatic organisms and plays a critical role in species distribution and abundance. Particularly during the warmer seasons, variations in habitat temperature may introduce episodes of stressful temperatures which the organisms must adapt to and compensate for to maintain physiological homeostasis. The marine environment ...
    • Experimental challenge of atlantic cod (Gadus morhua) with a brucella pinnipedialis strain from hooded seal (Cystophora cristata) 

      Nymo, Ingebjørg Helena; Seppola, Marit; Sascha, Al Dahouk; Bakkemo, Katrine Ryvold Arnesen; Jiménez de Bagüés, María Pilar; Godfroid, Jacques; Larsen, Anett Kristin (Peer reviewed; Journal article; Tidsskriftsartikkel, 2016-07-14)
      Pathology has not been observed in true seals infected with Brucella pinnipedialis. A lack of intracellular survival and multiplication of B. pinnipedialis in hooded seal (Cystophora cristata) macrophages in vitro indicates a lack of chronic infection in hooded seals. Both epidemiology and bacteriological patterns in the hooded seal point to a transient infection of environmental origin, possibly ...
    • Marine Mammal Brucella Reference Strains Are Attenuated in a BALB/c Mouse Model 

      Nymo, Ingebjørg Helena; Arias, Maykel; Pardo, Julian; Álvarez, María Pilar; Alcaraz, Ana; Godfroid, Jacques; Jiménez de Bagüés, María Pilar (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-03-09)
      Brucellosis is a zoonosis of worldwide distribution with numerous animal host species. Since the novel isolation of Brucella spp. from marine mammals in 1994 the bacteria have been isolated from various marine mammal hosts. The marine mammal reference strains Brucella pinnipedialis 12890 (harbour seal, Phoca vitulina) and Brucella ceti 12891 (harbour porpoise, Phocoena phocoena) were included in ...